Some of the work we’ve contributed to.
High-throughput identification of human SNPs affecting regulatory element activity
Joris van Arensbergen, Ludo Pagie, Vincent D FitzPatrick, Marcel de Haas, Marijke P Baltissen, Federico Comoglio, Robin H van der Weide, Hans Teunissen, Urmo Võsa, Lude Franke, Elzo de Wit, Michiel Vermeulen, Harmen J Bussemaker, Bas van Steensel. Nature Genetics. 2019 Jun 14; 51(7): 1160–1169. doi: 10.1038/s41588-019-0455-2
Reading ADP-ribosylation signaling using chemical biology and interaction proteomics
Katarzyna W Kliza , Qiang Liu , Laura W M Roosenboom , Pascal W T C Jansen , Dmitri V Filippov , Michiel Vermeulen. Nature Communications 2018 Apr 25;9(1):1653. doi: 10.1038/s41467-018-04084-0.
Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease
Visscher M, De Henau S, Wildschut MHE, van Es RM, Dhondt I, Michels H, Kemmeren P, Nollen EA, Braeckman BP, Burgering BMT, Vos HR, Dansen TB. Cell Rep. 2016 Sep 13;16(11):3041-3051. doi: 10.1016/j.celrep.2016.08.025. PMID: 27626671.
The interactome of a family of potential methyltransferases in HeLa cells
Valentina V. Ignatova, Pascal W. T. C. Jansen, Marijke P. Baltissen, Michiel Vermeulen, Robert Schneider. Science Reports. 2019; 9: 6584. doi: 10.1038/s41598-019-43010-2. PMID: 31036863
PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation
Evan Healy, Marlena Mucha, Eleanor Glancy, Darren J Fitzpatrick, Eric Conway, Hannah K Neikes, Craig Monger, Guido Van Mierlo, Marijke P Baltissen, Yoko Koseki, Michiel Vermeulen 2 , Haruhiko Koseki, Adrian P Bracken. Molecular Cell. 2021 Nov 4;81(21):4552-4567.e8. doi: 10.1016/j.molcel.2021.08.037.
The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes
Joep Joosten, Pascal Miesen, Ezgi Taşköprü, Bas Pennings, Pascal W T C Jansen, Martijn A Huynen, Michiel Vermeulen, Ronald P Van Rij. Nucleic Acids Research. 2019 Mar: 18;47(5):2546-2559. doi: 10.1093/nar/gky1266.
Characterization of a genomic region 8 kb downstream of GFI1B associated with myeloproliferative neoplasms
Maaike G J M van Bergen, Rinske van Oorschot, Saskia M Bergevoet, Aniek O de Graaf, Evelyn L R T M Tönnissen, Ellen Stevens-Linders, Kornelia Neveling, Pascal W T C Jansen, Marijke P A Baltissen, Michiel Vermeulen, Amit Mandoli, Joost H A Martens, Frank Preijers, Joop H Jansen, Bert A van der Reijden. Biochim Biophys Acta Mol Basis Dis. 2021 Dec 1;1867(12):166259. doi: 10.1016/j.bbadis.2021.166259.
Bifunctional protein PCBD2 operates as a co-factor for hepatocyte nuclear factor 1β and modulates gene transcription
Lotte E Tholen, Caro Bos, Pascal W T C Jansen, Hanka Venselaar, Michiel Vermeulen, Joost G J Hoenderop, Jeroen H F de Baaij. FASEB Journal. 2021 Apr;35(4):e21366. doi: 10.1096/fj.202002022R.
Proteomic Profiling of Two Distinct Populations of Extracellular Vesicles Isolated from Human Seminal Plasma
Xiaogang Zhang, Harmjan R Vos, Weiyang Tao, Willem Stoorvogel. Int J Mol Sci. 2020 Oct 26;21(21):7957. doi: 10.3390/ijms21217957.
The Human 2-Cys Peroxiredoxins form Widespread, Cysteine-Dependent- and Isoform-Specific Protein-Protein Interactions
Loes van Dam, Marc Pagès-Gallego, Paulien E Polderman, Robert M van Es, Boudewijn M T Burgering, Harmjan R Vos, Tobias B Dansen. Antioxidants (Basel). 2021 Apr 20;10(4):627. doi: 10.3390/antiox10040627.
Global profiling of protein-DNA and protein-nucleosome binding affinities using quantitative mass spectrometry
Matthew M Makowski, Cathrin Gräwe, Benjamin M Foster, Nhuong V Nguyen, Till Bartke, Michiel Vermeulen. Nature Communications. 2018 Apr 25;9(1):1653. doi: 10.1038/s41467-018-04084-0.
BANP opens chromatin and activates CpG-island-regulated genes
Ralph S Grand, Lukas Burger, Cathrin Gräwe, Alicia K Michael, Luke Isbel, Daniel Hess, Leslie Hoerner, Vytautas Iesmantavicius, Sevi Durdu, Marco Pregnolato, Arnaud R Krebs, Sébastien A Smallwood, Nicolas Thomä, Michiel Vermeulen, Dirk Schübeler. Nature. 2021 Aug;596(7870): 133-137. doi: 10.1038/s41586-021-03689-8.
Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets
Rinske van Oorschot, Marten Hansen, Johanna M Koornneef, Anna E Marneth, Saskia M Bergevoet, Maaike G J M van Bergen, Floris P J van Alphen, Carmen van der Zwaan, Joost H A Martens, Michiel Vermeulen, Pascal W T C Jansen, Marijke P A Baltissen, Britta A P Laros-van Gorkom, Hans Janssen, Joop H Jansen, Marieke von Lindern, Alexander B Meijer, Emile van den Akker, Bert A van der Reijden. Haematologica. . 2019 Jul;104(7):1460-1472. doi: 10.3324/haematol.2018.194555
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona
Wu J, Raas MWD, Alcaraz PS, Vos HR, Tromer EC, Snel B, Kops GJPL. J Cell Biol. 2024 Jan 1;223(1):e202303007. doi: 10.1083/jcb.202303007. Epub 2023 Nov 7.
FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer
Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation
Tavares S, Liv N, Pasolli M, Opdam M, Rätze MAK, Saornil M, Sluimer LM, Hengeveld RCC, van Es R, van Werkhoven E, Vos H, Rehmann H, Burgering BMT, Oosterkamp HM, Lens SMA, Klumperman J, Linn SC, Derksen PWB. Cell Reports 2022 Apr 5
Mocholi E, Russo L, Gopal K, Ramstead AG, Hochrein SM, Vos HR, Geeven G, Adegoke AO, Hoekstra A, van Es RM, Pittol JR, Vastert S, Rutter J, Radstake T, van Loosdregt J, Berkers C, Mokry M, Anderson CC, O'Connell RM, Vaeth M, Ussher J, Burgering BMT, Coffer PJ Cell Reports 2023 Jun 27;42(6):112583. doi: 10.1016/j.celrep.2023.112583. Epub 2023 Jun 1.